October 26, 2021

Health Club

The Health Look

Best Resveratrol Supplements: Review the Top 19 Product Picks

Resveratrol is one of the most popular antioxidant compounds available today.

Many people take resveratrol daily for weight loss, inflammation, diabetes, anti-aging, and even anti-cancer effects.

Science shows that resveratrol can impact inflammation throughout the body, which could make it a powerful way to support health and wellness.

With so many resveratrol supplements available, it’s difficult to know which one is right for you. Keep reading to discover our list of the best resveratrol supplements of 2021.

Ranking the Best Resveratrol Supplements in 2021

Every resveratrol supplement claims to support inflammation throughout the body. However, not all resveratrol supplements are made equal.

After contacting manufacturers, checking lab reports, and consulting with our editorial team, here’s how we ranked the best resveratrol supplements of 2021:

  • Nuzena Resveratrol Rapid +
  • Zenith Labs Longevity Activator
  • Revitaa Pro
  • Cymbiotika NMN
  • Reserveage Resveratrol
  • Thorne Research ResveraCel
  • Designs for Health Resveratrol Supreme
  • Garden of Life Raw Resveratrol
  • Toniq Resveratrol
  • Biotivia Transmax
  • Toniq Elixr
  • Life Extension Optimized Resveratrol
  • Purely Beneficial Resveratrol 1450
  • MAAC10 Trans-Resveratrol
  • Juvenon’s BloodFlow-7
  • LiGenics
  • Vivo Tonic
  • Claritox Pro
  • The Red Wine Diet

Nuzena Resveratrol Rapid +

Nuzena’s Resveratrol Rapid + is a resveratrol supplement that offers better value than most other resveratrol supplements on this list. Nuzena claims the formula can support healthy blood pressure, support insulin sensitivity, and support antioxidant effects for anti-aging and longevity.

Made in the United States, Resveratrol Rapid + contains a higher dose of resveratrol than any other supplement on our list: each capsule of Resveratrol Rapid + contains 1,200mg of resveratrol (giving you 50% trans-resveratrol content overall). That’s 10x to 20x the dose of other leading resveratrol supplements here – and hundreds of times the dose found in the average glass of red wine.

If you want a no-nonsense resveratrol supplement with a strong dose at a reasonable price, then you can’t do better than Nuzena’s Resveratrol +. It’s the best resveratrol supplement you can buy online today.

Price: $35 – get it here now

Longevity Activator

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Zenith Labs’ Longevity Activator uses resveratrol to promote anti-aging benefits throughout your body. Priced at $49 per bottle, Longevity Activator contains a moderate dose of resveratrol to promote anti-aging effects on your brain and body. Longevity Activator is also one of the few supplements on this list formulated by doctors, giving the formula an extra layer of legitimacy.

One of the top reasons why this resveratrol supplement gains one of the best ranking picks to use and buy is that Longevity Activator contains far more than just resveratrol too. In addition to 25mg of resveratrol, the formula includes 25mg to 100mg of green tea leaf extract, taurine, astragalus root, berberine, ashwagandha root, Asian ginseng root, turmeric, L-carnosine, and more.

Zenith Labs recommends taking one capsule of Longevity Activator daily to activate your body’s natural anti-aging properties. The McHenry, Illinois-based company uses a medical advisory board, including Dr. Ryan Shelton, to ensure each supplement passes strict quality standards. When factoring in all of the most critical research available, the Longevity Activator supplement with resveratrol is made by one of the most trusted and longest standing brands in the space and offers a great money back guarantee on all purchases.

Price: $49 – get it here now

Revitaa Pro

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Revitaa Pro is an all-natural stress reliever that promotes heart health and weight loss and leads with one primary ingredient, you guessed it, Japanese knotweed and resveratrol. Each capsule contains a range of ingredients to support inflammation in various ways. Although primarily advertised as a weight loss aid, Revitaa Pro may be able to revitalize your entire body in multiple ways. Plus, all purchases are backed by a 60 day moneyback guarantee.

Priced at $66 per bottle, Revitaa Pro contains just one active ingredient: resveratrol. Like other resveratrol supplements listed here, Revitaa Pro is focused on giving your body the highest possible dose of resveratrol while maximizing bioavailability. Although it’s not an instant weight loss cure, Revitaa Pro could help support various health and wellness benefits while lowering stress and weight. In truth, Revitaa Pro is our sleeper of all the best resveratrol supplements as it is specifically designed to give the resveratrol users seek while being formulated to act as a natural stress reliever, supporting healthy weight management and heart health. The official website is flooded with real testimonials of how well this resveratrol product works for those who have used it thus far. With zero side effects of using this resveratrol supplement and no product scam complaints to speak of (assuming order directly through the company), Revitaa Pro is the best resveratrol supplement for men and women of all ages looking for a multi-factor formula that delivers the prized nutrient and a host of other benefits.

As low as $52 per – get it here now

Cymbiotika NMN

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Cymbiotika’s NMN contains trans-resveratrol and L-theanine as its two active ingredients. Priced at $77 per bottle, NMN is one of the costlier options on our list. However, Cymbiotika backs up that price with strong doses of bioavailable resveratrol and is coupled with a strong NAD+ booster ingredient lineup.

Each two capsule serving of Cymbiotika NMN contains 400mg of nicotinamide mononucleotide (NMN) mixed with 100mg of resveratrol. Other ingredients include 200mg of green tea extract, 100mg of green coffee bean extract, and 200mg of apigenin. It’s not just a resveratrol supplement: it’s a collection of inflammation-supporting supplement ingredients that could help support overall health and wellness.

The primary goal of Cymbiotika NMN is to promote anti-aging effects by giving you an anti-aging molecule. NMN raises levels of NAD+ within the body. NAD+ is associated with anti-aging effects. By taking Cymbiotika NMN daily, you may be able to support cardiovascular health, DNA health, and overall anti-aging health, among other benefits.

Price: $77 – get it here now

Reserveage Resveratrol

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Reserveage’s Resveratrol formula gives you 500mg of resveratrol per serving to support heart health, cellular health, aging, weight loss, and more.

Each veggie capsule of Reserveage Resveratrol contains 800mg of a proprietary formula with Japanese knotweed extract, red wine grape extract (from skin, seeds, fruits, stems, and vines), and whole red grape. Together, these ingredients have been standardized to contain 500mg of trans-resveratrol per capsule, giving you an identical dose of trans-resveratrol to other top-ranked options on our list.

If you want to maximize the dose of resveratrol for maximum health supporting benefits, then Reserveage’s Resveratrol may be the right choice for you. By taking the formula daily, you may be able to support anti-aging effects, heart health, weight loss, and more – all while using Japanese knotweed red wine grapes, and other ingredients rich with natural resveratrol.

Price: $34 – get it here now

Thorne Research ResveraCel

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Thorne Research’s ResveraCel supports healthy aging with nicotinamide riboside, resveratrol, quercetin, and betaine anhydrous, some of the most popular anti-aging supplement ingredients available today. Each bottle contains 60 capsules of premium formula for $48.

Like other resveratrol and anti-aging supplements on this list, ResveraCel is marketed specifically to those who want to boost NAD+ levels. NAD+ is a molecule associated with aging. By promoting levels of NAD+, you may be able to turn back the clock on certain effects of aging.

Thorne Research is also one of the most trusted brands in the premium supplement space. The company is trusted by 100+ pro teams, and they also collaborate with Mayo Clinic on wellness research. Plus, they’re a partner of 11 United States Olympic teams. For all of these reasons and more, Thorne Research’s ResveraCel is one of the best resveratrol supplements you can buy today, even if it contains a lower dose of resveratrol (150mg) than other top-ranked options on our list.

Price: $48 – get it here now

Designs for Health Resveratrol Supreme

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Designs for Health’s Resveratrol Supreme is a resveratrol and quercetin supplement that delivers strong doses of its two active ingredients. Together, these ingredients can support healthy aging, cardiovascular health, cognitive health, and more by reducing free radicals.

The resveratrol in Resveratrol Supreme comes from Japanese knotweed, one of the richest natural sources of resveratrol. By combining 200mg of trans-resveratrol with 200mg of quercetin, Resveratrol Supreme can give your body the antioxidants it needs to support health and wellness in various ways.

We also like Designs for Health for its longstanding commitment to creating quality supplements. The company has sold supplements since 1989, making them one of the oldest resveratrol supplement companies listed here. With transparent dosing and science, top-quality ingredients, and reputable advertising, Designs for Health’s Resveratrol Supreme is one of the best resveratrol supplements you can buy today.

Price: $61 – get it here now

Garden of Life Raw Resveratrol

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The aptly-named Raw Resveratrol from Garden of Life is a natural resveratrol supplement priced at just $35. Each serving of Raw Resveratrol supports healthy aging, supports digestive health, and promotes overall health and wellness by targeting oxidative stress and other aspects of health.

What makes Raw Resveratrol unique from other ingredients listed here is the use of probiotics and digestive enzymes to support the targeted benefits. Each capsule of Raw Resveratrol contains 350mg of trans-resveratrol mixed with dozens of antioxidant-rich fruits and vegetables, 16mg of digestive enzymes, and 500 million CFUs of probiotics.

The trans-resveratrol in Raw Resveratrol comes from organic cabernet sauvignon grapes and fermented Japanese knotweed root, two of the most popular natural sources of resveratrol. With rich levels of multiple antioxidant-heavy ingredients, Raw Resveratrol is a resveratrol supplement with a surprisingly powerful punch.

Price: $35 – get it here now

Toniq Resveratrol

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Toniq’s Resveratrol is an ultra high purity resveratrol formula that distinguishes itself from competitors based on value alone: at just $20 for 60 capsules, Toniq’s Resveratrol has a price that’s tough to beat. Plus, further discounts are available when buying the 180 capsule bottle.

Each serving of Toniq Resveratrol contains 600mg of 98% pure trans-resveratrol from Japanese knotweed root extract. There are no other active ingredients. Although that sounds like a higher dose than other resveratrol supplements on our list, it’s a similar dose per capsule (300mg of trans-resveratrol per capsule) as other top-ranked options.

If you want a no-nonsense resveratrol supplement at a rock-bottom price with surprisingly strong dosages, then Toniq’s Resveratrol is one of the best options available today.

Price: $20 – get it here now

Transmax

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Transmax is a resveratrol supplement that contains 500mg of trans-resveratrol per serving with a 98% concentration. Biotivia has also added polydatin to enhance the bioavailability of the resveratrol, which means your body can absorb more of the resveratrol than it normally would.

By taking Transmax daily, you can purportedly support cellular health and body function at the cellular level. And, unlike other resveratrol supplements listed here, Transmax contains two ingredients specifically for bioavailability, including black pepper extract and polydatin. Together, these two ingredients can increase the amount of resveratrol that your body absorbs, which means more of the active effects end up affecting your body.

For trusted quality and a high-quality formula, Transmax is one of the best options in the resveratrol supplement space today. Plus, with 500mg of trans-resveratrol per serving, it competes with the top-ranked options on our list in terms of dosage – although the price is slightly higher than competing options above.

Price: $74 – get it here now

Toniq Elixr

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Elixr is the second Toniq supplement on our list. Featuring 90 capsules with NMN and resveratrol, Elixr has resveratrol, nicotinamide mononucleotide (NMN), and betaine anhydrous to maximize anti-aging effects.

Each three capsule serving of Elixr contains 500mg of resveratrol standardized to a 98% concentration, along with high doses each of NMN and betaine anhydrous. You take three capsules one to two times daily to support inflammation and maximize anti-aging benefits.

If you like the idea of Toniq Resveratrol but want more anti-aging benefits and ingredients, then Toniq Elixr may be the right choice for you. With strong doses of two additional ingredients, Elixr could help maximize antioxidant effects in multiple ways, giving you relief from the effects of aging – all at a reasonable price of $47.

Price: $47 – get it here now

Life Extension Optimized Resveratrol

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Life Extension’s Optimized Resveratrol is a convenient and affordable resveratrol supplement made by one of the better-known names in the supplement space. Priced at $32 per bottle, Optimized Resveratrol contains 250mg of trans-resveratrol per capsule derived from Japanese knotweed. The supplement also contains an additional 150mg of quercetin and 85mg of berry and fruit extract, among other ingredients, to maximize the antioxidant and anti-aging effects.

Life Extension markets Optimized Resveratrol as a way to promote youthful gene expression, support healthy insulin response, and support healthy inflammation responses, among other benefits. By taking Optimized Resveratrol daily, you could enjoy all of these benefits while promoting anti-aging effects.

Price: $32 – get it here now

Purely Beneficial Resveratrol 1450

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Purely Beneficial’s Resveratrol 1450 is one of the strongest and best-value resveratrol supplements on this list. Priced at $26 per bottle and backed by 7,000+ reviews on Amazon (with a stellar 4.6 star out of 5 rating), Purely Beneficial’s Resveratrol 1450 promotes anti-aging and cardiovascular health, among other benefits.

Each two capsule serving of Resveratrol 1450 contains 605mg of a trans resveratrol complex with Japanese knotweed extract, delivering a strong daily dose of trans-resveratrol to support anti-aging effects. To enhance the effectiveness of this formula further, Purely Beneficial has added 725mg of a polyphenol complex with green tea leaf extract, grape seed extract, acai fruit extract, red wine extract, and other beneficial plant-based ingredients.

Although it doesn’t contain 1450mg of resveratrol per serving, Resveratrol 1450 is one of the best options for those looking for a powerful resveratrol supplement from a reputable company.

Price: $26 – get it here now

MAAC10 Trans-Resveratrol

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MAAC10 makes a resveratrol supplement with 500mg of 99% pure trans-resveratrol extract in each two capsule serving. To enhance the bioavailability of this resveratrol, MAAC10 has even added black pepper extract (Bioperine), which has been shown to enhance your body’s absorption of certain ingredients.

With 250mg of trans-resveratrol per capsule, MAAC10’s Trans-Resveratrol competes with some of the higher-ranked supplements on our list. The formula has transparent ingredients and dosages and reasonable benefits claims – all things we look for when comparing resveratrol supplements online.

Plus, MAAC10 backs all purchases with a 60 day moneyback guarantee. If you don’t experience the heart, inflammation, brain, detoxification, and energy effects of MAAC10’s Trans-Resveratrol, then you’re entitled to a complete refund with no questions asked.

Price: $30 – get it here now

BloodFlow-7

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Many people take resveratrol for its effects on cardiovascular health. Studies show that resveratrol supplements could help with cardiovascular health, blood pressure, and cholesterol, among other metrics. BloodFlow-7 is a resveratrol supplement advertised primarily as a cardiovascular supplement. By taking Juvenon’s BloodFlow-7 daily, you can promote healthy blood flow and circulation using L-citrulline and trans-resveratrol.

According to Juvenon, BloodFlow-7 can open arteries by 62%, giving you healthy blood pressure. It can also eliminate swollen feet and aching legs, boost energy and stamina, sharpen memory and focus, and slow down aging, among other benefits.

To do that, BloodFlow-7 contains ingredients like resveratrol that promote nitric oxide (NO) levels. NO is associated with relaxed and widened blood vessels. To do that, BloodFlow-7 contains S7 (a blend of seven plant-based ingredients) with resveratrol, green tea leaf extract, beet root extract, and other ingredients. With 30mg of trans-resveratrol per serving, BloodFlow-7 could support blood flow in multiple ways using multiple proven ingredients.

Price: $30 – get it here now

LiGenics

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LiGenics is a metabolism formula that uses resveratrol and a dozen other ingredients to support overall health and wellness. With 40mg of resveratrol in each two capsule serving, LiGenics doesn’t compete with some of the top-ranked options on our list. However, the supplement combines this resveratrol with milk thistle, cayenne, ginseng, berberine, green tea extract, and alpha lipoic acid, among other ingredients.

LiGEnics is advertised primarily as a weight loss aid. By taking two capsules of LiGenics daily, you can purportedly optimize metabolism and lose a significant amount of weight – all with limited diet and exercise required. If you want to maximize the weight loss effects of resveratrol with a quality formula, then the made-in-the USA LiGenics may be the right choice for you.

Price: $59 – get it here now

Vivo Tonic

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Vivo Tonic is a blood sugar support supplement that uses resveratrol and other active ingredients. The 11-in-1 formula uses resveratrol, vitamins, minerals, and plant extracts to support blood sugar in various ways.

By taking two capsules of Vivo Tonic daily, you can purportedly use the same formula prized by monks in Kathmandu to keep their bodies in balance. Derived from an ancient Buddhist formula, Vivo Tonic claims to balance the body using a range of popular ingredients.

Active ingredients within Vivo Tonic include corosolic acid, banaba leaf, silymarin, berberine, ginseng, and other ingredients. The makers of Vivo Tonic describe some of these ingredients as “blood sugar regulators” because they’ve been used for centuries to balance blood sugar and cardiovascular health. The manufacturer claims the resveratrol in Vivo Tonic will “normalize” blood sugar. However, at $79 per bottle and with limited dosage or ingredient information disclosed upfront, it’s difficult to rank Vivo Tonic higher than other resveratrol supplements listed here.

Price: $79 – get it here now

Claritox Pro

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Claritox Pro is a health supplement created by Jim Benson. Jim added chromium, zinc, green tea, berberine, resveratrol, milk thistle, cayenne, ginseng, and banaba extract to a formula. Today, Jim sells Claritox Pro online as a way to support overall health and wellness.

Priced at $69 per bottle, Claritox Pro claims to support health and wellness in multiple ways. Each two capsule serving contains 40mg of resveratrol along with vitamins, minerals, plants, and herbs to support other aspects of health and wellness. Although the manufacturer provides limited evidence about how the supplement works or what it does, Claritox Pro is popular online for its ability to support health.

Price: $69 – get it here now

Bonus Guide: The Red Wine Diet

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Although not a supplement, The Red Wine Diet is a guide created by a certified strength and conditioning specialist. In the guide, you’ll discover how a diet rich with red wine could support inflammation throughout your body, helping you lose weight and enjoy other benefits.

In The Red Wine Diet, you’ll discover the benefits of resveratrol and other components in red wine. While most diets encourage you to stop drinking altogether, The Red Wine Diet advocates adding red wine to your diet (or at least maintaining your current consumption).

Inside The Red Wine Diet, you’ll discover a collection of eBooks covering everything you need to know about the diet and how it works. You get a list of foods that can sabotage weight loss, for example, and other habits that may be inhibiting weight loss results. You can also discover weight loss accelerators, step-by-step weight loss guides, and specific meal plans, among other perks.

Price: $15 – get it here now

How We Ranked

Every resveratrol supplement claims to give your body antioxidants to target inflammation. However, not all resveratrol supplements are made equal. Some are better than others.

To separate the best and worst resveratrol supplements, our editorial team considered all of the following:

Resveratrol Dosage: You’re buying a resveratrol supplement for the resveratrol. That’s why resveratrol dosage was one of our most important ranking factors. The higher the resveratrol dosage, the more active ingredients end up in your body. The top-ranked resveratrol supplements on our list have dosages of 200mg to 500mg of resveratrol per capsule, while lower-ranked resveratrol supplements have dosages of 10mg to 40mg.

Complementary Ingredients: Although resveratrol is the most important ingredient in a resveratrol supplement, we also considered complementary ingredients in our rankings. Some ingredients (like black pepper extract or Bioperine) boost the absorption of resveratrol, for example, while other ingredients complement the effects of resveratrol. With their own antioxidant capabilities.

Ingredient Transparency & Labelling: Some resveratrol supplements use proprietary labels or unclear labeling to hide their origins, concentration, and ingredient sources. We preferred resveratrol supplements with transparent labeling.

Price & Value: Some people want to pay $70 for a one month supply of a supplement, while others want to pay $20. We featured several resveratrol supplements for all different budgets, although we emphasized good value at every price to ensure users got the most bang for their buck.

Advertised Benefits & Honesty: Resveratrol has been linked to anti-cancer effects in some small studies. However, that doesn’t mean resveratrol supplements can advertise themselves as a cure for cancer. Some studies show resveratrol can help with weight loss, but that doesn’t mean you’ll lose 30lbs in a week with no diet or exercise. We were wary of resveratrol supplements that made dishonest claims about their ability to treat or prevent diseases. By FDA regulations, supplement cannot advertise themselves as a treatment, cure, or preventative measure for diseases or illnesses.

Manufacturer Reputation & History: Good resveratrol supplement companies have a proven track record of creating effective supplements with transparent ingredients at an approved location. We weren’t biased against new resveratrol supplement companies. However, we preferred companies with the highest degrees of quality and transparency.

What is Resveratrol?

Resveratrol is a plant-based chemical with antioxidant properties. Strong doses of resveratrol are found in red wine, grapes, and certain berries and peanuts.

Instead of drinking 100 glasses of red wine per day for resveratrol, some people take resveratrol supplements to get an equivalent dose. A resveratrol supplement contains a concentrated, high dose of resveratrol. This dose may support inflammation throughout the body, helping to support various benefits.

The average glass of red wine contains around 0.5mg of resveratrol. In comparison, the top-ranked resveratrol supplements on our list contain 250mg to 500mg of resveratrol per serving. It’s like drinking 50 to 100 glasses of red wine!

Resveratrol is found in particularly high concentration in the skins and seeds of grapes and berries. Some supplements get their resveratrol from grape skin extract, for example. Others get it from other parts of grapes or berries.

Benefits of Resveratrol: What Does Science Say?

There’s evidence showing that resveratrol can support various benefits. Although some studies have been performed on humans, others have been performed on animals or human cells in test tubes. We’ll review that evidence below to share the best, most science-backed benefits of resveratrol.

Resveratrol is best-known for its anti-aging benefits. Many people take resveratrol supplements daily for their purported effects on aging, lifespan, wrinkles, and more.

Studies have shown that resveratrol could extend lifespan and support various anti-aging benefits. In this study, for example, researchers found that resveratrol activated certain genes that fight off diseases and aging. A similar study found that taking a resveratrol supplement was similar to restricting calories: both restricting calories and taking resveratrol appear to extend lifespan.

One of the biggest and most-shared reviews on resveratrol was published in 2016. Researchers reviewed evidence on resveratrol and concluded that resveratrol increased lifespan in 60% of the organisms studied. This effect was most prominent in organisms with little relation to humans (like worms and fish). However, it’s possible resveratrol exhibits some type of lifespan-increasing effect.

Many people take resveratrol supplements for cardiovascular health and blood pressure. Some studies show resveratrol can help lower blood pressure. In this 2015 review, researchers found that high doses of resveratrol could help reduce the pressure exerted on artery walls when the heart beats, also known as your systolic blood pressure (the upper number in your blood pressure readings). This number increases with age as arteries stiffen. When the number is high, it indicates a higher risk of heart disease.

Researchers believe resveratrol impacts cardiovascular health by raising nitric oxide (NO) levels in the bloodstream. Your body produces nitric oxide to widen and relax blood vessels. When you have higher levels of NO, you tend to have lower blood pressure. In this 2008 study published in Hypertension, researchers found that wine polyphenols (including resveratrol) improved blood vessel performance in rats with high blood pressure.

Resveratrol also seems to have a positive effect on blood fats (i.e. your cholesterol). Several studies have shown that resveratrol supplements could change blood fats in a healthy way. In this 2014 study, for example, researchers gave resveratrol to mice with cholesterol issues, finding that resveratrol effectively reduced blood lipid levels in mice. Similarly, this 2016 study found that resveratrol lowered cholesterol levels in mice even when they were fed a high-fat diet. Researchers found that resveratrol reduced the body weight and total cholesterol levels of mice while increasing levels of ‘good’ (HDL) cholesterol.

Researchers believe resveratrol affects cholesterol by oxidizing ‘bad’ (LDL) cholesterol in your bloodstream. As resveratrol travels through your bloodstream, it neutralizes and destroys bad cholesterol, including the LDL oxidation that builds plaque within your artery walls.

Researchers have observed the cholesterol lowering effects of resveratrol in humans. In this study, researchers gave participants a high dose of resveratrol daily for six months. After six months, researchers found that ‘bad’ (LDL) cholesterol had dropped by 4.5% and oxidized LDL had dropped 20% compared to participants taking a placebo.

Resveratrol is also prized for its neuroprotective effects. Many people take resveratrol supplements to support brain health, ward off the cognitive effects of aging, and support overall cognition. Multiple studies have shown that red wine can slow down cognitive decline, and many researchers believe this effect is attributed to resveratrol. In this 2014 study, for example, researchers found that the resveratrol in red wine appeared to slow the progression of Alzheimer’s disease and other degenerative brain conditions.

Researchers believe resveratrol impacts Alzheimer’s disease because of its effects on beta-amyloids. Beta-amyloids are chemicals that form plaque within the blood vessels of the brain, increasing the progression of Alzheimer’s disease. The antioxidant effects of resveratrol could fight this plaque, reducing the progression of Alzheimer’s.

Other studies show resveratrol could help with diabetes. Although most studies have occurred on animals, studies suggest that resveratrol may help increase insulin sensitivity. To do that, resveratrol appears to stop an enzyme from turning glucose into sorbitol, a sugar alcohol. Sorbitol causes oxidative stress in diabetics, making the condition worse.

Resveratrol could help diabetics in other ways. In one review study, researchers found that resveratrol helps people with diabetes in multiple areas of the body. Researchers found resveratrol can protect against oxidative stress, decrease inflammation, and activate AMPK in diabetics, for example.

Others take resveratrol to ease joint pain. Studies suggest that resveratrol could target inflammation within the joints, increasing mobility and reducing pain. In this study, for example, researchers found that resveratrol may help cartilage from deteriorating. Cartilage breakdown is one of the main causes of joint pain. In another study, researchers injected resveratrol directly into the knee joints of rabbits with arthritis and found they experienced less damage to cartilage.

One of the most important areas of resveratrol research lies in its anti-cancer effects. Multiple studies have suggested that resveratrol could inhibit cancer cell growth, change the gene expression of cancer cells to inhibit growth, and affect cancer in other ways. In separate studies, resveratrol has been shown to fight several types of cancer cells, including gastric, colon, skin, breast, and prostate cancers. In most of these studies, researchers found that resveratrol inhibited cancer cell growth, which could help prevent cancer cells from replicating and spreading.

One of the biggest problems with resveratrol is its bioavailability. Some researchers believe your body doesn’t absorb resveratrol easily. In this 2011 study, for example, researchers found that little resveratrol is absorbed by your body when taking resveratrol supplements orally. However, researchers and supplement companies are constantly searching for new ways to make resveratrol more bioavailable.

Overall, resveratrol is an exciting area of research. However, we need more large scale research in humans to verify these effects. As more research on resveratrol gets revealed, we’re learning more about its powerful health supporting properties.

Resveratrol Dosage

Most resveratrol supplements contain 50mg to 300mg of resveratrol per serving. The best resveratrol supplement contain 250mg to 600mg of resveratrol per serving.

Some experts believe you can experience the benefits of resveratrol with as little as 5 to 10mg per day. Other studies have tested doses as high as 2,500mg or 5,000mg.

For most purposes, however, you can enjoy the benefits of resveratrol with a dose of around 10mg to 50mg per day.

Taking higher doses of resveratrol may not be a good idea. In this 2016 study, for example, researchers found participants developed a fever when taking more than 1,500mg of resveratrol daily for six months. Similarly, this study found that taking 2,500mg of resveratrol daily for an extended period was linked with nausea, vomiting, diarrhea, and liver dysfunction.

Other studies, however, have shown that resveratrol is safe to take even in doses up to 5,000mg per day.

Side Effects of Resveratrol

Studies on resveratrol have revealed few major risks. When used by healthy adults in normal dosages, resveratrol is tolerated well by adults.

However, there’s limited information about the safe dose of resveratrol for humans. There’s also limited research on resveratrol’s interactions with medications.

In high doses, resveratrol could reduce the clotting ability of blood, which could increase bleeding or bruising. This could cause interactions with anti-clotting drugs like heparin or warfarin. Talk to your doctor before taking resveratrol if you are taking medication or have any type of medical condition.

One study found that resveratrol was a “double edged sword” because it was associated with health problems at higher dosages. Researchers found that taking 2.5g of resveratrol or more per day was associated with nausea, vomiting, diarrhea, and liver dysfunction. Another study, however, found that a 5g daily dose of resveratrol was safe for most healthy adults.

Overall, most people experience zero side effects when taking normal doses of resveratrol.

FAQs About Resveratrol

We get plenty of questions about resveratrol. Here’s how our experts answered some of the most common questions about resveratrol.

Q: What is resveratrol?

A: Resveratrol is a plant compound that functions like an antioxidant.

Q: Where does resveratrol come from?

A: Resveratrol is found in high concentrations in red grapes, grape skins, and certain types of berries and peanuts.

Q: How do resveratrol supplements work?

A: Resveratrol supplements seem to work by supporting inflammation and oxidation throughout your body. Some studies show resveratrol targets plaque, bad cholesterol, nitric oxide levels, and other aspects of health and wellness.

Q: What do resveratrol supplements do?

A: People take resveratrol supplements daily for everything from anti-aging effects to anti-cancer effects. Studies suggest that resveratrol supplements support blood pressure, cardiovascular health, inflammation, diabetes symptoms, blood sugar, anti-aging effects, and more.

Q: How does resveratrol work as an antioxidant?

A: Resveratrol is part of the polyphenols’ stilbenoids group, where two phenol rings are connected by an ethylene bridge. Plants produce the chemical as a natural protective measure. When plants are stressed, they produce resveratrol as a phytoalexin – a type of protective antibiotic. Plants may release phytoalexins like resveratrol to recover from fungal attacks, UV radiation, and other attacks.

Q: Why is red wine healthy?

A: Some studies suggest that red wine supports health because it contains some dose of resveratrol.

Q: Can resveratrol help with cancer?

A: Some small studies have shown that resveratrol kills cancer cells or helps with cancer in other ways. However, we need more research, especially large scale research in humans, to verify these effects.

Q: Does resveratrol help with blood pressure?

A: Studies show that resveratrol may help with blood pressure by raising nitric oxide levels, relaxing vessel walls, and supporting other aspects of cardiovascular health.

Q: Does resveratrol help with cholesterol?

A: Studies have shown that resveratrol neutralizes bad cholesterol while promoting good cholesterol, which could make it an effective supplement for people with high cholesterol.

Q: Does resveratrol help with dementia and Alzheimer’s disease?

A: Studies show that resveratrol could help with dementia and Alzheimer’s disease by targeting plaque that builds up within the blood vessels of the brain. Some studies have shown that taking resveratrol supplements daily could slow the progression of the disease.

Q: How do I take resveratrol?

A: Some people take resveratrol in the form of a supplement. You can find resveratrol supplements in capsules or powders. Others take berries, grapes, wine, blueberries, cranberries, pomegranates, or fruit juices daily for resveratrol.

Q: What are the benefits of resveratrol?

A: Resveratrol has gained a lot of attention for its effects on aging, heart disease, diabetes, cancer, Alzheimer’s, and weight loss, among other conditions. Since many diseases and illnesses are linked to inflammation, some people also believe that resveratrol can help with other conditions.

Q: What are the best food sources of resveratrol?

A: The best food sources of resveratrol include grape skins, grape seeds, peanuts, pistachios, mulberries, cranberries, and blueberries.

Q: Can resveratrol help with weight loss?

A: Some studies suggest that resveratrol could help with weight loss. Antioxidant-rich foods and beverages appear to support weight loss, making it easier to lose weight and keep it off.

Q: What’s the best resveratrol supplement?

A: Any of the resveratrol supplements at the top of our list should be among the best resveratrol supplements available today.

Q: What’s the best time to take resveratrol?

A: There’s no research suggesting that it’s better to take resveratrol at certain times of the day. You can take resveratrol at any time of the day to enjoy its potential benefits.

Q: How much resveratrol is in red wine?

A: The average red wine contains around 2mg of resveratrol per liter, or around 0.5mg in a typical glass of red wine.

Q: What’s the difference between resveratrol and trans-resveratrol?

A: You can find two different types of resveratrol, including resveratrol and trans-resveratrol. Trans-resveratrol is a more bioactive form of the natural chemical, and it’s the type of resveratrol found in most nutritional supplements daily. Ordinary resveratrol (also known as cis-resveratrol) is still bioactive and still has antioxidant properties, although it doesn’t appear to have as many benefits as trans-resveratrol. Trans-resveratrol is made from the trans isomers of resveratrol, while cis-resveratrol is made from the cis isomers.

Q: What are the benefits of trans-resveratrol?

A: Trans-resveratrol has all of the same benefits as resveratrol, including its ability to support inflammation, blood pressure, cardiovascular health, brain health, weight loss, diabetes symptoms, and more. Trans-resveratrol is the more bioactive form of resveratrol, and studies suggest it helps support inflammation in various ways.

Final Word

Resveratrol is a natural compound linked to powerful benefits. By taking a resveratrol supplement daily, you may be able to support weight loss, cardiovascular health, brain health, or even anti-cancer effects, among other benefits.

There are many options when choosing the best resveratrol product to supplement with, but there is no doubt the best of the best are here on the top ranking formulas today:

Not all resveratrol supplements are made equal. To find the best resveratrol supplements available today, check our list above.

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Disclaimer:

Please understand that any advice or guidelines revealed here are not even remotely a substitute for sound medical advice from a licensed healthcare provider. Make sure to consult with a professional physician before making any purchasing decision if you use medications or have concerns following the review details shared above. Individual results may vary as the statements made regarding these products have not been evaluated by the Food and Drug Administration. The efficacy of these products has not been confirmed by FDA-approved research. These products are not intended to diagnose, treat, cure or prevent any disease.

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